POLYMERS Vol.72 No.8
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COVER STORY
Visualization of Structures and Dynamics of Proteins
As one type of macromolecules playing a central role in biological functions, proteins are important research targets not only in chemistry but also in biology. The “structures” and “dynamics” of protein molecules are closely related to their “functions,” and irreversible aggregation due to denaturation causes diseases. Crystallographic analysis has revealed the beautiful three-dimensional structures of proteins, allowing for the understanding of life phenomena and the development of drugs. In recent years, it has been shown that the semi-fluidic assembly of proteins, liquid-liquid phase separation, is involved in various biological functions such as signal transduction, therefore the “dynamics” of proteins have also attracted increasing attention. In this issue, we focus on the rapidly developing techniques for protein structure and dynamics analysis, and the new forms and functions of proteins that are being revealed based on these techniques.
Editors: MURAOKA, KAMIKAWA, TAKEDA, and T. NISHIMURA

Digest for English Readers
368

Hot Topics in Polymer Science in SPSJ
371
SPSJ PMF Poster Awards 2022

Commentary
Progress of Structure and Dynamics Analysis of Proteins based on Advances in Analytical Instruments Tetsuo ASAKURA
372

COVER STORY: Highlight Reviews
Liquid-Liquid Phase Separation Based on Protein Phase Transition and Solution Mutual Solubility Akira NOMOTO, Kentaro SHIRAKI
373
Molecular Features of Calcium Pumps Revealed by Cryo-EM Analysis Kenji INABA
376
Recent Progress in Protein Labeling Techniques for Live-Cell Imaging Takuya KAMIKAWA, Yuichiro HORI
379

PolyMANGA
382

COVER STORY: Topics and Products
Conformational Study of Multi-Domain Proteins Using Paramagnetic Lanthanide Ions Tomohide SAIO
383
Analysis of Binding Dynamics between Ion Channel and Ligand by High-Speed Atomic Force Microscopy Ayumi SUMINO
385
Dynamics of Proteins in Solution as Seen by Neutron Scattering Rintaro INOUE
387
Observing Macromolecular Assemblies by Cryo-Electron Microscopy Takeshi YOKOYAMA
389

Polymer Science and I: A Personal Account
My Steps from NANO to POLY Asae ITO
391

Messages: “Work and Life”
Grateful for In-Person Meetings Kira B. LANDENBERGER
392

Front-Line Polymer Science
π-Stacked Cyclic Oligomers and Macrocycles Yasuhiro MORISAKI
393

Messages from SPSJ
398
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