POLYMERS Vol.63 No.10 |
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COVER STORY Re-Programming of Macromolecules |
Functions involved in biomacromolecules such as proteins are programmed as a sequence of the monomers that construct them. Therefore, if we can freely re-program their sequences, the functions of biomacromolecules may be artificially controlled. In that sense, sequences themselves are the intrinsic structural factor of macromolecules that determines their functions. Furthermore in the field of synthetic polymers, recent advances in the polymerization technology enable to control the sequence of polymers. However, it is extremely difficult to predict functions and higher-ordered structures of the polymers from their sequences only. Accordingly, a lot of new methodologies are proposed to control the sequences in order to create high functionalities. In this special issue entitled “re-programing of macromolecules”, recent progress on the new strategies for controlling the sequences of macromolecules are introduced. Editors: ASANUMA, OUCHI, and SERIZAWA |
Digest for English Readers | 706
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Hot Topics in Polymer Science in SPSJ | 710
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Commentary |
Molecular Re-Programing to Expose Hidden Biofunctions | Masahiko SISIDO | 711
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COVER STORY: Highlight Reviews |
Ribosomal Synthesis of Functional Macrocyclic Polypeptides and RaPID Discovery of Bioactive Polypeptides | Hiroaki SUGA, Toru YOSHITOMI, Masanobu NAGANO | 712
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Precision Control of Monomer Sequences in Vinyl Copolymers | Kotaro SATOH, Masami KAMIGAITO | 715 |
Reprogramming of Nucleic Acid Ligands: “Aptamers” | Kazunori IKEBUKURO, Nasa SAVORY, Koichi ABE | 718 |
PolyMANGA | 721 |
COVER STORY: Topics and Products |
Expansion of Genetic Code and Protein Function | Takahiro HOHSAKA | 722 |
Bipedal Walking Template toward Sequence-Controlled Vinyl Polymers | Makoto OUCHI | 724 |
Design of Functional Peptides Using Informational Analysis | Hiroyuki HONDA | 726 |
Preparation of Polymer Aptamer from a Copolymer Library | Yu HOSHINO | 728 |
Creation of Nucleic Acid Aptamers That Contain Unnatural Nucleotides | Masayasu KUWAHARA | 730 |
Polymer Science and I: A Personal Account |
Still Growing Up? | Hiromu KASHIDA | 732
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Messages: “Work and Life” |
Have a Flexible Work-Life Balance | Rika IWAURA | 733
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Front-Line Polymer Science |
Past, Present and Future of Single Polymer Chain Mechanics | Ken NAKAJIMA, Xiaobin LIANG | 734
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From My Bookshelf | Eiji IHARA / Sakiko TSUJI | 738 |
Messages from SPSJ | 739 |
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