POLYMERS Vol.63 No.10
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COVER STORY
Re-Programming of Macromolecules
Functions involved in biomacromolecules such as proteins are programmed as a sequence of the monomers that construct them. Therefore, if we can freely re-program their sequences, the functions of biomacromolecules may be artificially controlled. In that sense, sequences themselves are the intrinsic structural factor of macromolecules that determines their functions. Furthermore in the field of synthetic polymers, recent advances in the polymerization technology enable to control the sequence of polymers. However, it is extremely difficult to predict functions and higher-ordered structures of the polymers from their sequences only. Accordingly, a lot of new methodologies are proposed to control the sequences in order to create high functionalities. In this special issue entitled “re-programing of macromolecules”, recent progress on the new strategies for controlling the sequences of macromolecules are introduced.
Editors: ASANUMA, OUCHI, and SERIZAWA
Digest for English Readers
706

Hot Topics in Polymer Science in SPSJ
710

Commentary
Molecular Re-Programing to Expose Hidden Biofunctions Masahiko SISIDO
711

COVER STORY: Highlight Reviews
Ribosomal Synthesis of Functional Macrocyclic Polypeptides and RaPID Discovery of Bioactive Polypeptides Hiroaki SUGA, Toru YOSHITOMI, Masanobu NAGANO
712
Precision Control of Monomer Sequences in Vinyl Copolymers Kotaro SATOH, Masami KAMIGAITO
715
Reprogramming of Nucleic Acid Ligands: “Aptamers” Kazunori IKEBUKURO, Nasa SAVORY, Koichi ABE
718

PolyMANGA
721

COVER STORY: Topics and Products
Expansion of Genetic Code and Protein Function Takahiro HOHSAKA
722
Bipedal Walking Template toward Sequence-Controlled Vinyl Polymers Makoto OUCHI
724
Design of Functional Peptides Using Informational Analysis Hiroyuki HONDA
726
Preparation of Polymer Aptamer from a Copolymer Library Yu HOSHINO
728
Creation of Nucleic Acid Aptamers That Contain Unnatural Nucleotides Masayasu KUWAHARA
730

Polymer Science and I: A Personal Account
Still Growing Up? Hiromu KASHIDA
732

Messages: “Work and Life”
Have a Flexible Work-Life Balance Rika IWAURA
733

Front-Line Polymer Science
Past, Present and Future of Single Polymer Chain Mechanics Ken NAKAJIMA, Xiaobin LIANG
734

From My Bookshelf Eiji IHARA / Sakiko TSUJI
738

Messages from SPSJ
739
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